LEXICON PHARMACEUTICALS, INC. - LXRX

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q3 2026 · Compare: Q2 2026
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
Artal Group S.A. History No change 175,156,062 420,374 45.15% 45.15% 1 0 0.0% Q2 2026 Aug 13, 2026
FMR LLC History No change 51,782,045 124,276 0.01% 0.01% 2 0 0.0% Q2 2026 Aug 13, 2026
Siren, L.L.C. History No change 44,303,518 106,328 2.15% 2.15% 3 0 0.0% Q2 2026 Aug 13, 2026
Sessa Capital IM, L.P. History No change 18,960,836 45,506 0.76% 0.76% 4 0 0.0% Q2 2026 Aug 14, 2026
BlackRock, Inc. History No change 17,348,741 41,636 0.0% 0.0% 5 0 0.0% Q2 2026 Aug 07, 2026
VANGUARD CAPITAL MANAGEMENT LLC History No change 9,901,208 23,762 0.0% 0.0% 6 0 0.0% Q2 2026 Aug 13, 2026
Point72 Asset Management, L.P. History No change 8,251,325 19,803 0.02% 0.02% 7 0 0.0% Q2 2026 Aug 14, 2026
GEODE CAPITAL MANAGEMENT, LLC History No change 6,244,372 14,989 0.0% 0.0% 8 0 0.0% Q2 2026 Aug 12, 2026
STATE STREET CORP History No change 4,917,769 11,802 0.0% 0.0% 9 0 0.0% Q2 2026 Sep 22, 2026
VANGUARD PORTFOLIO MANAGEMENT LLC History No change 2,357,749 5,658 0.0% 0.0% 10 0 0.0% Q2 2026 Aug 13, 2026
CITADEL ADVISORS LLC History No change 1,988,382 4,772 0.0% 0.0% 11 0 0.0% Q2 2026 Sep 02, 2026
NORTHERN TRUST CORP History No change 1,968,619 4,724 0.0% 0.0% 12 0 0.0% Q2 2026 Aug 13, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History No change 1,956,775 4,696 0.0% 0.0% 13 0 0.0% Q2 2026 Aug 14, 2026
VANGUARD FIDUCIARY TRUST CO History No change 1,634,571 3,922 0.0% 0.0% 14 0 0.0% Q2 2026 Aug 13, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History No change 1,383,176 3,319 0.0% 0.0% 15 0 0.0% Q2 2026 Aug 14, 2026
Ishara Investments LP History No change 1,271,000 3,050 2.24% 2.24% 16 0 0.0% Q2 2026 Aug 14, 2026
MILLENNIUM MANAGEMENT LLC History No change 1,134,229 2,722 0.0% 0.0% 17 0 0.0% Q2 2026 Aug 14, 2026
RENAISSANCE TECHNOLOGIES LLC History No change 1,127,000 2,704 0.0% 0.0% 18 0 0.0% Q2 2026 Aug 13, 2026
ADAR1 Capital Management, LLC History No change 750,000 1,800 0.08% 0.08% 19 0 0.0% Q2 2026 Aug 14, 2026
ACADIAN ASSET MANAGEMENT LLC History No change 696,617 1,666 0.0% 0.0% 20 0 0.0% Q2 2026 Aug 13, 2026
UBS Group AG History No change 684,713 1,643 0.0% 0.0% 21 0 0.0% Q2 2026 Aug 13, 2026
TWO SIGMA INVESTMENTS, LP History No change 643,444 1,544 0.0% 0.0% 22 0 0.0% Q2 2026 Aug 14, 2026
Nuveen, LLC History No change 586,664 1,407 0.0% 0.0% 23 0 0.0% Q2 2026 Aug 11, 2026
JANE STREET GROUP, LLC History No change 582,900 1,398 0.0% 0.0% 24 0 0.0% Q2 2026 Aug 14, 2026
Bank of New York Mellon Corp History No change 568,706 1,364 0.0% 0.0% 25 0 0.0% Q2 2026 Aug 06, 2026
Invesco Ltd. History No change 508,071 1,219 0.0% 0.0% 26 0 0.0% Q2 2026 Aug 14, 2026
GOLDMAN SACHS GROUP INC History No change 485,546 1,165 0.0% 0.0% 27 0 0.0% Q2 2026 Aug 14, 2026
BANK OF AMERICA CORP /DE/ History No change 421,299 1,011 0.0% 0.0% 28 0 0.0% Q2 2026 Aug 14, 2026
GSA CAPITAL PARTNERS LLP History No change 397,219 953 0.06% 0.06% 29 0 0.0% Q2 2026 Aug 06, 2026
BARCLAYS PLC History No change 387,483 929 0.0% 0.0% 30 0 0.0% Q2 2026 Aug 14, 2026
Compagnie Lombard Odier SCmA History No change 480,000 900 0.01% 0.01% 31 0 0.0% Q3 2026 Nov 04, 2026
XTX Topco Ltd History No change 357,877 858 0.01% 0.01% 32 0 0.0% Q2 2026 Aug 14, 2026
Janney Montgomery Scott LLC History No change 295,548 709 0.0% 0.0% 33 0 0.0% Q2 2026 Aug 05, 2026
PROFUND ADVISORS LLC History Added to 340,479 638 0.02% 0.0% 34 +291,893 600.78% Q3 2026 Oct 28, 2026
CANADA PENSION PLAN INVESTMENT BOARD History No change 257,900 618 0.0% 0.0% 35 0 0.0% Q2 2026 Aug 14, 2026
RHUMBLINE ADVISERS History No change 256,885 616 0.0% 0.0% 36 0 0.0% Q2 2026 Aug 11, 2026
DEUTSCHE BANK AG\ History No change 247,528 594 0.0% 0.0% 37 0 0.0% Q2 2026 Aug 07, 2026
WELLS FARGO & COMPANY/MN History No change 230,470 553 0.0% 0.0% 38 0 0.0% Q2 2026 Aug 14, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History No change 204,391 491 0.0% 0.0% 39 0 0.0% Q2 2026 Aug 14, 2026
WELLINGTON MANAGEMENT GROUP LLP History No change 179,700 431 0.0% 0.0% 40 0 0.0% Q2 2026 Aug 14, 2026
GROUP ONE TRADING LLC History No change 175,013 420 0.0% 0.0% 41 0 0.0% Q2 2026 Aug 13, 2026
Virtus Investment Advisers, LLC History No change 170,415 408 0.1% 0.1% 42 0 0.0% Q2 2026 Aug 11, 2026
Scheeler Financial LLC History New 217,452 407 0.31% — 43 +217,452 New Q3 2026 Oct 13, 2026
Headlands Technologies LLC History No change 167,198 401 0.04% 0.04% 44 0 0.0% Q2 2026 Aug 12, 2026
Ikarian Capital, LLC History No change 164,674 395 0.04% 0.04% 45 0 0.0% Q2 2026 Aug 14, 2026
Quarry LP History No change 156,186 374 0.03% 0.03% 46 0 0.0% Q2 2026 Aug 14, 2026
MetLife Investment Management, LLC History No change 146,410 351 0.0% 0.0% 47 0 0.0% Q2 2026 Aug 13, 2026
MORGAN STANLEY History No change 132,902 318 0.0% 0.0% 48 0 0.0% Q2 2026 Aug 13, 2026
PANAGORA ASSET MANAGEMENT INC History No change 132,042 316 0.0% 0.0% 49 0 0.0% Q2 2026 Aug 06, 2026
CITIGROUP INC History Reduced 154,665 289 0.0% 0.0% 51 -20,540 -11.72% Q3 2026 Nov 04, 2026
JPMORGAN CHASE & CO History No change 109,839 289 0.0% 0.0% 50 0 0.0% Q2 2026 Aug 12, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History No change 114,114 273 0.0% 0.0% 52 0 0.0% Q2 2026 Aug 14, 2026
Cornerstone Investment Partners, LLC History No change 113,739 272 0.01% 0.01% 53 0 0.0% Q2 2026 Aug 07, 2026
Cerity Partners LLC History No change 98,400 236 0.0% 0.0% 54 0 0.0% Q2 2026 Aug 14, 2026
ALGERT GLOBAL LLC History No change 92,150 221 0.0% 0.0% 55 0 0.0% Q2 2026 Aug 13, 2026
BANK OF NOVA SCOTIA History No change 86,607 207 0.0% 0.0% 56 0 0.0% Q2 2026 Aug 12, 2026
LPL Financial LLC History No change 84,916 203 0.0% 0.0% 57 0 0.0% Q2 2026 Aug 07, 2026
Vanguard Global Advisers, LLC History No change 77,946 187 0.0% 0.0% 58 0 0.0% Q2 2026 Aug 13, 2026
AQR CAPITAL MANAGEMENT LLC History No change 75,230 180 0.0% 0.0% 59 0 0.0% Q2 2026 Aug 14, 2026
Police & Firemen's Retirement System of New Jersey History No change 73,402 176 0.0% 0.0% 60 0 0.0% Q2 2026 Jul 23, 2026
PRUDENTIAL FINANCIAL INC History No change 71,345 171 0.0% 0.0% 61 0 0.0% Q2 2026 Aug 12, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History No change 69,747 167 0.0% 0.0% 62 0 0.0% Q2 2026 Sep 09, 2026
NEW YORK STATE COMMON RETIREMENT FUND History No change 68,400 164 0.0% 0.0% 63 0 0.0% Q2 2026 Jul 29, 2026
TWO SIGMA SECURITIES, LLC History No change 66,375 159 0.01% 0.01% 64 0 0.0% Q2 2026 Aug 14, 2026
SEI INVESTMENTS CO History No change 63,937 153 0.0% 0.0% 65 0 0.0% Q2 2026 Aug 14, 2026
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO History Added to 71,428 133 0.02% 0.02% 66 +1 0.0% Q3 2026 Nov 03, 2026
R Squared Ltd History No change 54,985 131 0.07% 0.07% 67 0 0.0% Q2 2026 Aug 05, 2026
Vanguard Personalized Indexing Management, LLC History No change 54,334 130 0.0% 0.0% 68 0 0.0% Q2 2026 Aug 11, 2026
State of New Jersey Common Pension Fund D History New 68,142 127 0.0% — 69 +68,142 New Q3 2026 Nov 05, 2026
Fortis Group Advisors, LLC History No change 50,000 120 0.02% 0.02% 70 0 0.0% Q2 2026 Jul 24, 2026
Schonfeld Strategic Advisors LLC History No change 49,435 118 0.0% 0.0% 71 0 0.0% Q2 2026 Aug 14, 2026
SCOTIA CAPITAL INC. History No change 48,871 117 0.0% 0.0% 72 0 0.0% Q2 2026 Aug 11, 2026
Straight Path Wealth Management History No change 62,666 117 0.03% 0.04% 73 0 0.0% Q3 2026 Oct 23, 2026
VOYA INVESTMENT MANAGEMENT LLC History No change 47,771 114 0.0% 0.0% 74 0 0.0% Q2 2026 Aug 12, 2026
Arizona State Retirement System History New 59,532 111 0.0% — 75 +59,532 New Q3 2026 Nov 03, 2026
AXQ CAPITAL, LP History No change 45,727 109 0.01% 0.01% 76 0 0.0% Q2 2026 Aug 06, 2026
BOOTHBAY FUND MANAGEMENT, LLC History No change 44,315 106 0.0% 0.0% 77 0 0.0% Q2 2026 Aug 14, 2026
ALLIANCEBERNSTEIN L.P. History No change 67,800 105 0.0% 0.0% 78 0 0.0% Q2 2026 Aug 14, 2026
WINTON GROUP Ltd History No change 43,200 103 0.0% 0.0% 79 0 0.0% Q2 2026 Aug 07, 2026
INTECH INVESTMENT MANAGEMENT LLC History No change 42,491 101 0.0% 0.0% 80 0 0.0% Q2 2026 Aug 10, 2026
LMR Partners LLP History No change 41,091 98 0.0% 0.0% 81 0 0.0% Q2 2026 Aug 14, 2026
BANK OF MONTREAL /CAN/ History No change 40,000 96 0.0% 0.0% 82 0 0.0% Q2 2026 Aug 12, 2026
BNP PARIBAS FINANCIAL MARKETS History No change 37,780 90 0.0% 0.0% 83 0 0.0% Q2 2026 Aug 13, 2026
Rafferty Asset Management, LLC History No change 34,090 81 0.0% 0.0% 84 0 0.0% Q2 2026 Aug 14, 2026
Pathstone Holdings, LLC History No change 29,969 71 0.0% 0.0% 85 0 0.0% Q2 2026 Aug 13, 2026
VIRGINIA RETIREMENT SYSTEMS ET Al History New 35,300 66 0.0% — 86 +35,300 New Q3 2026 Oct 28, 2026
SECURITY NATIONAL BANK OF SIOUX CITY IOWA /IA/ History No change 26,650 63 0.03% 0.03% 87 0 0.0% Q2 2026 Sep 18, 2026
Legal & General Group Plc History No change 24,185 58 0.0% 0.0% 88 0 0.0% Q2 2026 Aug 14, 2026
VICTORY CAPITAL MANAGEMENT INC History No change 24,223 58 0.0% 0.0% 89 0 0.0% Q2 2026 Aug 07, 2026
SIMPLEX TRADING, LLC History Added to 29,921 56 0.0% 0.0% 91 +21,381 250.36% Q3 2026 Nov 04, 2026
Graham Capital Management, L.P. History No change 23,541 56 0.0% 0.0% 90 0 0.0% Q2 2026 Aug 14, 2026
Ameritas Investment Partners, Inc. History No change 22,986 55 0.0% 0.0% 92 0 0.0% Q2 2026 Aug 13, 2026
ProShare Advisors LLC History Reduced 28,509 53 0.0% 0.0% 95 -4,079 -12.52% Q3 2026 Oct 28, 2026
PINNACLE ASSOCIATES LTD History Reduced 28,615 53 0.0% 0.0% 93 -400 -1.38% Q3 2026 Oct 20, 2026
D. E. Shaw & Co., Inc. History No change 22,200 53 0.0% 0.0% 94 0 0.0% Q2 2026 Aug 14, 2026
Quadrature Capital Ltd History No change 21,998 52 0.0% 0.0% 96 0 0.0% Q2 2026 Aug 06, 2026
PRINCIPAL FINANCIAL GROUP INC History Added to 26,226 49 0.0% 0.0% 97 +7,192 37.79% Q3 2026 Nov 02, 2026
TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC History No change 20,000 48 0.0% 0.0% 98 0 0.0% Q2 2026 Aug 10, 2026
DIKER MANAGEMENT LLC History No change 20,000 48 0.04% 0.04% 99 0 0.0% Q2 2026 Aug 14, 2026
Caitong International Asset Management Co., Ltd History Added to 25,326 47 0.0% — 101 +25,169 16031.21% Q3 2026 Oct 29, 2026
Russell Investments Group, Ltd. History No change 19,902 47 0.0% 0.0% 100 0 0.0% Q2 2026 Aug 06, 2026
Tower Research Capital LLC (TRC) History No change 19,486 46 0.0% 0.0% 102 0 0.0% Q2 2026 Aug 11, 2026
CREDIT AGRICOLE S A History No change 18,975 45 0.0% 0.0% 103 0 0.0% Q2 2026 Aug 14, 2026
Creative Planning History New 23,242 43 0.0% — 104 +23,242 New Q3 2026 Nov 02, 2026
XPONANCE LLC History Reduced 22,210 41 0.0% 0.0% 105 -1,553 -6.54% Q3 2026 Nov 03, 2026
Pictet Asset Management Holding SA History New 21,835 40 0.0% — 106 +21,835 New Q3 2026 Nov 03, 2026
WEDBUSH SECURITIES INC History No change 20,000 38 0.0% 0.0% 107 0 0.0% Q3 2026 Oct 22, 2026
Invera Wealth Advisors, LLC History No change 20,000 37 0.02% 0.03% 108 0 0.0% Q3 2026 Oct 28, 2026
CAPTRUST FINANCIAL ADVISORS History No change 15,321 36 0.0% 0.0% 109 0 0.0% Q2 2026 Aug 13, 2026
Callan Family Office, LLC History No change 14,090 33 0.0% 0.0% 110 0 0.0% Q2 2026 Aug 11, 2026
Gotham Asset Management, LLC History No change 13,627 32 0.0% 0.0% 111 0 0.0% Q2 2026 Aug 14, 2026
CIBC Bancorp USA Inc. History No change 13,740 32 0.0% 0.0% 112 0 0.0% Q2 2026 Aug 13, 2026
ROYAL BANK OF CANADA History No change 12,650 30 0.0% 0.0% 113 0 0.0% Q2 2026 Aug 14, 2026
State of Wyoming History Reduced 15,012 28 0.0% 0.03% 116 -104,078 -87.39% Q3 2026 Oct 28, 2026
HBK Sorce Advisory LLC History No change 11,786 28 0.0% 0.0% 114 0 0.0% Q2 2026 Aug 06, 2026
Squarepoint Ops LLC History No change 11,741 28 0.0% 0.0% 115 0 0.0% Q2 2026 Aug 14, 2026
TRUIST FINANCIAL CORP History No change 14,000 26 0.0% 0.0% 117 0 0.0% Q3 2026 Oct 30, 2026
Mariner, LLC History No change 11,239 26 0.0% 0.0% 118 0 0.0% Q2 2026 Aug 13, 2026
Perennial Investment Advisors, LLC History No change 10,990 26 0.0% 0.0% 119 0 0.0% Q2 2026 Aug 14, 2026
Cetera Investment Advisers History No change 10,524 25 0.0% 0.0% 120 0 0.0% Q2 2026 Aug 12, 2026
CIBC Asset Management Inc History No change 13,102 24 0.0% 0.0% 121 0 0.0% Q3 2026 Nov 05, 2026
Berger Financial Group, Inc History No change 10,000 24 0.0% 0.0% 122 0 0.0% Q2 2026 Aug 04, 2026
Apollon Wealth Management, LLC History No change 11,378 21 0.0% 0.0% 123 0 0.0% Q3 2026 Oct 23, 2026
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC History Reduced 11,765 20 0.0% 0.0% 124 -374 -3.08% Q3 2026 Oct 13, 2026
NBT BANK, N.A. History No change 10,000 18 0.0% 0.0% 125 0 0.0% Q3 2026 Oct 21, 2026
Sterling Capital Management LLC History Added to 7,491 14 0.0% 0.0% 126 +6,617 757.09% Q3 2026 Oct 22, 2026
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM History No change 3,427 8 0.0% 0.0% 127 0 0.0% Q2 2026 Aug 24, 2026
SBI Securities Co., Ltd. History Reduced 4,208 7 0.0% 0.0% 128 -14,997 -78.09% Q3 2026 Oct 21, 2026
NISA INVESTMENT ADVISORS, LLC History Added to 3,646 6 0.0% 0.0% 129 +1,054 40.66% Q3 2026 Oct 20, 2026
PNC FINANCIAL SERVICES GROUP, INC. History No change 1,461 3 0.0% 0.0% 130 0 0.0% Q2 2026 Aug 07, 2026
Rialto Wealth Management, LLC History No change 1,313 3 0.0% 0.0% 131 0 0.0% Q2 2026 Aug 11, 2026
Global Retirement Partners, LLC History No change 1,000 2 0.0% 0.0% 132 0 0.0% Q2 2026 Aug 06, 2026
Avion Wealth History No change 1,115 2 0.0% 0.0% 133 0 0.0% Q3 2026 Nov 03, 2026
Physician Wealth Advisors, Inc. History No change 1,412 2 0.0% 0.0% 134 0 0.0% Q3 2026 Oct 20, 2026
BFC Planning, Inc. History No change 1,000 2 0.0% 0.0% 135 0 0.0% Q2 2026 Oct 29, 2026
MassMutual Private Wealth & Trust, FSB History No change 957 1 0.0% 0.0% 136 0 0.0% Q3 2026 Oct 05, 2026
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO History No change 500 1 0.0% 0.0% 137 0 0.0% Q2 2026 Aug 12, 2026
Fortitude Family Office, LLC History No change 706 1 0.0% 0.0% 138 0 0.0% Q3 2026 Oct 14, 2026
Cassaday & Co Wealth Management LLC History No change 1,000 1 0.0% 0.0% 139 0 0.0% Q3 2026 Oct 27, 2026
Aster Capital Management (DIFC) Ltd History No change 743 1 0.0% 0.0% 140 0 0.0% Q2 2026 Aug 14, 2026
Basecamp Wealth Advisors LLC History No change 691 1 0.0% 0.0% 141 0 0.0% Q2 2026 Aug 14, 2026
MACKENZIE FINANCIAL CORP History Closed out 0 0 — 0.0% — -963,354 -100.0% Q3 2026 Nov 02, 2026
Leonteq Securities AG History Closed out 0 0 — 0.0% — -30,000 -100.0% Q3 2026 Oct 29, 2026
Parkside Financial Bank & Trust History New 505 0 — — — +505 New Q3 2026 Oct 27, 2026
GAMMA Investing LLC History New 152 0 — — — +152 New Q3 2026 Oct 08, 2026
Covestor Ltd History Added to 184 0 — — — +103 127.16% Q3 2026 Oct 30, 2026
Larson Financial Group LLC History Closed out 0 0 — — — -100 -100.0% Q3 2026 Nov 05, 2026
JONES FINANCIAL COMPANIES LLLP History No change 356 0 — — — 0 0.0% Q2 2026 Aug 14, 2026
Clearstead Advisors, LLC History No change 100 0 — — — 0 0.0% Q2 2026 Aug 06, 2026
HM PAYSON & CO History No change 37 0 — — — 0 0.0% Q2 2026 Jul 17, 2026
Allworth Financial LP History No change 263 0 — — — 0 0.0% Q2 2026 Aug 11, 2026
Arax Advisory Partners History No change 41 0 — — — 0 0.0% Q2 2026 Aug 10, 2026
Blume Capital Management, Inc. History No change 5 0 — — — 0 0.0% Q3 2026 Oct 23, 2026
OSAIC HOLDINGS, INC. History No change 163 0 — — — 0 0.0% Q2 2026 Aug 14, 2026
Parallel Advisors, LLC History No change 247 0 — — — 0 0.0% Q3 2026 Nov 03, 2026
Steward Partners Investment Advisory, LLC History No change 400 0 — — — 0 0.0% Q2 2026 Aug 13, 2026
Rockefeller Capital Management L.P. History No change 300 0 — — — 0 0.0% Q2 2026 Aug 13, 2026
Farther Finance Advisors, LLC History No change 2 0 — — — 0 0.0% Q3 2026 Oct 08, 2026
SYNTAX RESEARCH, INC. History No change 142 0 — — — 0 0.0% Q3 2026 Nov 04, 2026