Lyell Immunopharma, Inc. - LYEL

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
ARCH Venture Management, LLC History No change 2,759,072 84,924 13.03% 9.1% 1 0 0.0% Q4 2025 Feb 17, 2026
GSK plc History New 1,512,659 46,559 5.83% 2 +1,512,659 New Q4 2025 Feb 12, 2026
MWG Caph Ltd History New 1,008,116 31,029 42.88% 3 +1,008,116 New Q4 2025 Feb 17, 2026
VANGUARD GROUP INC History Added to 826,430 25,437 0.0% 0.0% 4 +47,426 6.09% Q4 2025 Jan 29, 2026
Foresite Capital Management IV, LLC History No change 800,399 24,636 10.72% 7.12% 5 0 0.0% Q4 2025 Feb 17, 2026
Orland Properties Ltd History No change 754,698 23,229 4.35% 2.62% 6 0 0.0% Q4 2025 Feb 17, 2026
Decheng Capital LLC History Added to 692,050 21,301 2.87% 1.69% 7 +96,584 16.22% Q4 2025 Feb 12, 2026
Almitas Capital LLC History No change 577,807 17,784 3.92% 2.15% 8 0 0.0% Q4 2025 Feb 17, 2026
Foresite Capital Management V, LLC History No change 477,078 14,684 8.93% 7.12% 9 0 0.0% Q4 2025 Feb 17, 2026
CITADEL ADVISORS LLC History Reduced 340,701 10,486 0.0% 0.0% 10 -15,540 -4.36% Q4 2025 Feb 17, 2026
venBio Partners LLC History Reduced 337,697 10,394 4.81% 4.36% 11 -135,782 -28.68% Q4 2025 Feb 17, 2026
Alphabet Inc. History No change 293,256 9,026 0.35% 0.2% 12 0 0.0% Q4 2025 Feb 13, 2026
BlackRock, Inc. History Added to 181,837 5,596 0.0% 0.0% 13 +5,031 2.85% Q4 2025 Feb 12, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 162,997 5,019 0.0% 0.0% 14 +32,740 25.13% Q4 2025 Feb 09, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 159,416 4,906 0.0% 0.0% 15 +143,257 886.55% Q4 2025 Feb 17, 2026
HSG Holding Ltd History No change 152,299 3,935 0.21% 0.0% 16 0 0.0% Q4 2025 Feb 13, 2026
Invesco Ltd. History New 98,649 3,036 0.0% 17 +98,649 New Q4 2025 Feb 19, 2026
GOLDMAN SACHS GROUP INC History New 96,675 2,975 0.0% 18 +96,675 New Q4 2025 Mar 25, 2026
MIC Capital Management UK LLP History No change 87,028 2,678 0.61% 0.28% 19 0 0.0% Q4 2025 Feb 17, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 85,423 2,629 0.0% 0.0% 20 +5,913 7.44% Q4 2025 Feb 13, 2026
RBF Capital, LLC History Reduced 74,585 2,295 0.1% 0.07% 21 -21,046 -22.01% Q4 2025 Feb 17, 2026
MARSHALL WACE, LLP History New 73,315 2,256 0.0% 22 +73,315 New Q4 2025 Feb 13, 2026
MILLENNIUM MANAGEMENT LLC History Reduced 58,651 1,805 0.0% 0.0% 23 -66,710 -53.21% Q4 2025 Feb 17, 2026
JOHNSON & JOHNSON History No change 54,887 1,689 0.3% 0.18% 24 0 0.0% Q4 2025 Mar 18, 2026
STATE STREET CORP History Added to 51,472 1,584 0.0% 0.0% 25 +17,720 52.5% Q4 2025 Feb 13, 2026
MORGAN STANLEY History Added to 42,949 1,321 0.0% 0.0% 26 +5,929 16.02% Q4 2025 Feb 13, 2026
Ikarian Capital, LLC History Reduced 41,081 1,264 0.1% 0.07% 27 -2,718 -6.21% Q4 2025 Feb 18, 2026
RENAISSANCE TECHNOLOGIES LLC History Reduced 39,490 1,215 0.0% 0.0% 28 -24,500 -38.29% Q4 2025 Feb 12, 2026
CANADA PENSION PLAN INVESTMENT BOARD History Added to 32,111 988 0.0% 0.0% 29 +2,700 9.18% Q4 2025 Feb 17, 2026
NORTHERN TRUST CORP History Added to 30,280 932 0.0% 0.0% 30 +2,152 7.65% Q4 2025 Feb 17, 2026
Susquehanna Portfolio Strategies, LLC History No change 20,800 640 0.01% 0.01% 31 0 0.0% Q4 2025 Feb 17, 2026
Clarius Group, LLC History No change 19,958 614 0.04% 0.02% 32 0 0.0% Q4 2025 Jan 14, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History No change 18,000 554 0.01% 0.01% 33 0 0.0% Q4 2025 Feb 17, 2026
BARCLAYS PLC History Added to 15,967 491 0.0% 0.0% 34 +14,775 1239.51% Q4 2025 Feb 13, 2026
TWO SIGMA INVESTMENTS, LP History Reduced 15,616 480 0.0% 0.0% 35 -5,211 -25.02% Q4 2025 Feb 17, 2026
UBS Group AG History Reduced 13,203 406 0.0% 0.0% 36 -8,039 -37.84% Q4 2025 Jan 29, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History No change 13,128 405 0.0% 0.0% 37 0 0.0% Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History New 12,409 381 0.0% 38 +12,409 New Q4 2025 Feb 12, 2026
Point72 Asset Management, L.P. History New 11,480 353 0.0% 39 +11,480 New Q4 2025 Feb 17, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Reduced 9,516 292 0.0% 0.0% 40 -2,718 -22.22% Q4 2025 Feb 17, 2026
Qube Research & Technologies Ltd History New 9,051 278 0.0% 41 +9,051 New Q4 2025 Feb 17, 2026
ExodusPoint Capital Management, LP History New 8,511 261 0.0% 42 +8,511 New Q4 2025 Feb 17, 2026
BANK OF AMERICA CORP /DE/ History Added to 8,045 247 0.0% 0.0% 43 +3,366 71.94% Q4 2025 Feb 17, 2026
RAYMOND JAMES FINANCIAL INC History New 7,900 243 0.0% 44 +7,900 New Q4 2025 Feb 18, 2026
Candriam S.C.A. History New 7,617 234 0.0% 45 +7,617 New Q4 2025 Feb 13, 2026
BBR PARTNERS, LLC History New 6,834 210 0.01% 46 +6,834 New Q4 2025 Feb 11, 2026
CITIGROUP INC History Added to 4,233 130 0.0% 0.0% 47 +3,203 310.97% Q4 2025 Feb 13, 2026
DIADEMA PARTNERS LP History New 3,800 116 0.02% 48 +3,800 New Q4 2025 Feb 17, 2026
China Universal Asset Management Co., Ltd. History Added to 3,457 106 0.01% 0.0% 49 +90 2.67% Q4 2025 Jan 29, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 3,170 97 0.0% 0.0% 50 +2,815 792.96% Q4 2025 Feb 10, 2026
FMR LLC History Reduced 1,829 56 0.0% 0.0% 51 -893 -32.81% Q4 2025 Feb 17, 2026
ACADIAN ASSET MANAGEMENT LLC History Reduced 1,657 51 0.0% 0.0% 52 -9,733 -85.45% Q4 2025 Feb 10, 2026
JPMORGAN CHASE & CO History Added to 1,616 49 0.0% 0.0% 53 +1,126 229.8% Q4 2025 Feb 11, 2026
Tower Research Capital LLC (TRC) History Reduced 1,194 36 0.0% 0.0% 54 -664 -35.74% Q4 2025 Feb 17, 2026
JONES FINANCIAL COMPANIES LLLP History Reduced 1,025 31 0.0% 0.0% 55 -975 -48.75% Q4 2025 Feb 17, 2026
Mirae Asset Global Investments Co., Ltd. History Added to 1,031 31 0.0% 0.0% 56 +288 38.76% Q4 2025 Jan 26, 2026
Advisors Asset Management, Inc. History No change 567 17 0.0% 0.0% 57 0 0.0% Q4 2025 Feb 12, 2026
GF FUND MANAGEMENT CO. LTD. History Added to 416 12 0.0% 0.0% 58 +3 0.73% Q4 2025 Jan 27, 2026
WELLS FARGO & COMPANY/MN History New 125 3 0.0% 59 +125 New Q4 2025 Feb 13, 2026
OSAIC HOLDINGS, INC. History New 124 3 0.0% 61 +124 New Q4 2025 Feb 17, 2026
MAI Capital Management History No change 100 3 0.0% 0.0% 60 0 0.0% Q4 2025 Feb 13, 2026
SIMPLEX TRADING, LLC History Reduced 37 1 0.0% 0.0% 65 -125 -77.16% Q4 2025 Feb 11, 2026
Cornerstone Financial Management LLC History New 46 1 0.0% 68 +46 New Q4 2025 Feb 13, 2026
ROYAL BANK OF CANADA History New 24 1 0.0% 63 +24 New Q4 2025 Feb 17, 2026
CWM, LLC History Reduced 20 1 0.0% 0.0% 66 -22 -52.38% Q4 2025 Jan 26, 2026
US BANCORP \DE\ History No change 58 1 0.0% 62 0 0.0% Q4 2025 Jan 30, 2026
Daiwa Securities Group Inc. History No change 45 1 0.0% 0.0% 64 0 0.0% Q4 2025 Feb 11, 2026
GAMMA Investing LLC History No change 35 1 0.0% 67 0 0.0% Q4 2025 Jan 05, 2026
ORBIMED ADVISORS LLC History Closed out 0 0 0.02% -51,727 -100.0% Q3 2025 Nov 14, 2025
Trexquant Investment LP History Closed out 0 0 0.0% -10,275 -100.0% Q3 2025 Nov 14, 2025
Rangeley Capital, LLC History Closed out 0 0 0.14% -10,000 -100.0% Q3 2025 Nov 14, 2025
IFP Advisors, Inc History Closed out 0 0 -1 -100.0% Q3 2025 Feb 06, 2026
NISA INVESTMENT ADVISORS, LLC History No change 25 0 0 0.0% Q4 2025 Jan 15, 2026