Spyre Therapeutics, Inc. - SYRE
Insiders (Form 4) · last 180 days · showing up to 200 transactions
· Form 144 is shown in the SEC filings tab
· Updating…
Visible: 0
Transaction codes:
P = Open-market purchase ·
S = Open-market sale ·
A = Grant/award ·
M = Exercise/conversion of derivative ·
G = Gift ·
F = Tax withholding ·
J = Other ·
A/D:
A = Acquired (buy/receive) ·
D = Disposed (sell/give)
| Filed | Owner | Title | Code | A/D | Shares | Price | Value | Shares after | SEC |
|---|---|---|---|---|---|---|---|---|---|
| May 08, 2026 | — | S | D | 19,269.0 | 75.35 | 1,451,919.15 | 88,606.0 | View | |
| May 08, 2026 | — | S | D | 24,814.0 | 74.76 | 1,855,094.64 | 107,875.0 | View | |
| May 08, 2026 | — | S | D | 33,513.0 | 73.72 | 2,470,578.36 | 132,689.0 | View | |
| May 08, 2026 | — | S | D | 2,404.0 | 72.57 | 174,458.28 | 166,202.0 | View | |
| May 01, 2026 | Chief Medical Officer | M | D | 78,333.0 | 0.0 | 0.0 | 321,667.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 400.0 | 75.37 | 30,148.0 | 0.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 5,059.0 | 74.6 | 377,401.4 | 400.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 10,358.0 | 73.74 | 763,798.92 | 5,459.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 12,777.0 | 72.94 | 931,954.38 | 15,817.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 8,777.0 | 71.56 | 628,082.12 | 28,594.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 19,656.0 | 70.61 | 1,387,910.16 | 37,371.0 | View | |
| May 01, 2026 | Chief Medical Officer | S | D | 21,306.0 | 69.53 | 1,481,406.18 | 57,027.0 | View | |
| May 01, 2026 | Chief Medical Officer | M | A | 78,333.0 | 27.46 | 2,151,024.18 | 78,333.0 | View | |
| May 01, 2026 | Chief Financial Officer | M | D | 12,500.0 | 0.0 | 0.0 | 382,357.0 | View | |
| May 01, 2026 | Chief Financial Officer | S | D | 12,500.0 | 71.37 | 892,125.0 | 97,994.0 | View | |
| May 01, 2026 | Chief Financial Officer | M | A | 12,500.0 | 14.5 | 181,250.0 | 110,494.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 300.0 | 74.96 | 22,488.0 | 612,540.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 1,700.0 | 74.23 | 126,191.0 | 612,840.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 3,100.0 | 73.14 | 226,734.0 | 614,540.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 1,000.0 | 71.76 | 71,760.0 | 617,640.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 3,600.0 | 70.77 | 254,772.0 | 618,640.0 | View | |
| May 01, 2026 | Chief Executive Officer | S | D | 5,300.0 | 69.54 | 368,562.0 | 622,240.0 | View | |
| Apr 03, 2026 | Chief Medical Officer | M | D | 7,958.0 | 0.0 | 0.0 | 87,542.0 | View | |
| Apr 03, 2026 | Chief Medical Officer | S | D | 7,958.0 | 50.0 | 397,900.0 | 0.0 | View | |
| Apr 03, 2026 | Chief Medical Officer | M | A | 7,958.0 | 21.66 | 172,370.28 | 7,958.0 | View | |
| Apr 03, 2026 | Chief Executive Officer | S | D | 2,656.0 | 49.92 | 132,587.52 | 627,540.0 | View | |
| Apr 03, 2026 | Chief Executive Officer | S | D | 12,344.0 | 49.2 | 607,324.8 | 630,196.0 | View | |
| Apr 03, 2026 | Chief Financial Officer | M | D | 7,500.0 | 0.0 | 0.0 | 394,857.0 | View | |
| Apr 03, 2026 | Chief Financial Officer | S | D | 1,300.0 | 49.98 | 64,974.0 | 97,994.0 | View | |
| Apr 03, 2026 | Chief Financial Officer | S | D | 6,200.0 | 49.21 | 305,102.0 | 99,294.0 | View | |
| Apr 03, 2026 | Chief Financial Officer | M | A | 7,500.0 | 14.5 | 108,750.0 | 105,494.0 | View | |
| Mar 03, 2026 | Chief Financial Officer | M | D | 2,500.0 | 0.0 | 0.0 | 402,357.0 | View | |
| Mar 03, 2026 | Chief Financial Officer | S | D | 200.0 | 41.66 | 8,332.0 | 97,994.0 | View | |
| Mar 03, 2026 | Chief Financial Officer | S | D | 2,300.0 | 40.56 | 93,288.0 | 98,194.0 | View | |
| Mar 03, 2026 | Chief Financial Officer | M | A | 2,500.0 | 14.5 | 36,250.0 | 100,494.0 | View | |
| Mar 03, 2026 | Chief Executive Officer | S | D | 9,100.0 | 42.49 | 386,659.0 | 642,540.0 | View | |
| Mar 03, 2026 | Chief Executive Officer | S | D | 5,900.0 | 41.73 | 246,207.0 | 651,640.0 | View | |
| Feb 04, 2026 | Chief Executive Officer | S | D | 14,043.0 | 32.87 | 461,593.41 | 657,540.0 | View | |
| Feb 04, 2026 | Chief Executive Officer | S | D | 957.0 | 31.82 | 30,451.74 | 671,583.0 | View | |
| Jan 23, 2026 | — | J | A | 63,227.0 | 0.0 | 0.0 | 168,606.0 | View | |
| Jan 13, 2026 | See Remarks | A | A | 140,000.0 | 0.0 | 0.0 | 140,000.0 | View | |
| Jan 13, 2026 | Chief Financial Officer | A | A | 140,000.0 | 0.0 | 0.0 | 140,000.0 | View | |
| Jan 13, 2026 | Chief Executive Officer | A | A | 528,000.0 | 0.0 | 0.0 | 528,000.0 | View | |
| Jan 13, 2026 | Chief Medical Officer | A | A | 140,000.0 | 0.0 | 0.0 | 140,000.0 | View | |
| Jan 06, 2026 | Chief Executive Officer | S | D | 100.0 | 32.39 | 3,239.0 | 671,907.0 | View | |
| Jan 06, 2026 | Chief Executive Officer | S | D | 2,191.0 | 31.79 | 69,651.89 | 672,007.0 | View | |
| Jan 06, 2026 | Chief Executive Officer | S | D | 12,709.0 | 30.47 | 387,243.23 | 674,198.0 | View | |
| Dec 03, 2025 | Chief Executive Officer | S | D | 4,005.0 | 29.83 | 119,469.15 | 686,907.0 | View | |
| Dec 03, 2025 | Chief Executive Officer | S | D | 10,995.0 | 28.73 | 315,886.35 | 690,912.0 | View |