RA CAPITAL MANAGEMENT, L.P.
Q2 2025 13F-HR Holdings
Net value change ($000)
-52,232
(-0.9%)
New positions
6
Sold out positions
28
Turnover %
8.8%
Sector allocation + QoQ delta (equities-only)
Snapshot: Change Analysis
Compared to Q1 2025
Methodology:
sector metrics are equities-only;
instrument mix chart is ex-options;
options exposure is shown separately.
Why this matters.
Top Adds (Value $000, Stocks/ETFs)
| ASND | 172,112 | 10.7% |
| CDTX | 140,396 | 596.4% |
| SION | 71,968 | 65.9% |
| SPRY | 52,893 | 38.7% |
| 89bio, Inc. | 50,719 | 35.1% |
| FULC | 40,916 | 138.9% |
| TSHA | 39,301 | 260.0% |
| VOR | 35,781 | 125.8% |
| SEPN | 33,440 | 82.6% |
| RYTM | 29,131 | 9.0% |
Top Reduces (Value $000, Stocks/ETFs)
| PCVX | -71,248 | -15.5% |
| EWTX | -66,176 | -33.8% |
| APGE | -58,636 | -100.0% |
| ZLAB | -46,803 | -100.0% |
| RXST | -46,372 | -49.1% |
| DAWN | -45,642 | -100.0% |
| JANX | -43,640 | -14.4% |
| URGN | -35,461 | -100.0% |
| WAVE LIFE SCIENCES LTD | -28,759 | -19.6% |
| Astria Therapeutics, Inc. | -27,262 | -100.0% |
Instrument mix + QoQ Δ (ex-options)
How this table is calculated:
SEC
VALUE ($000) is used as reported.
For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received.
Column % is bucket-based:
non-options share is calculated inside non-option total, options share is calculated inside options total.
Details.
Filter:
Instrument:
| Issuer Name | Ticker | Sector | Industry | Class | History | Value ($000) | % | Shares | Shares Δ | Shares Δ% | Value Δ ($000) | Value Δ% | Principal | Option Type |
|---|