Pyxis Oncology, Inc. - PYXS

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 1 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
PFIZER INC History No change 7,032,770 8,087 3.42% 3.57% 1 0 0.0% Q4 2025 Feb 12, 2026
Laurion Capital Management LP History Added to 4,796,479 5,515 0.21% 0.14% 2 +1,170,505 32.28% Q4 2025 Feb 17, 2026
GordonMD Global Investments LP History New 4,121,870 4,740 3.4% 3 +4,121,870 New Q4 2025 Feb 17, 2026
VANGUARD GROUP INC History Added to 2,335,768 2,686 0.0% 0.0% 4 +171,806 7.94% Q4 2025 Jan 29, 2026
Palo Alto Investors LP History No change 1,037,421 1,193 0.17% 0.43% 5 0 0.0% Q4 2025 Feb 17, 2026
683 Capital Management, LLC History Added to 891,910 1,025 0.04% 0.06% 6 +366,910 69.89% Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History Added to 786,010 903 0.0% 0.0% 7 +482,310 158.81% Q4 2025 Feb 12, 2026
BlackRock, Inc. History Added to 784,077 901 0.0% 0.0% 8 +100,375 14.68% Q4 2025 Feb 12, 2026
MILLENNIUM MANAGEMENT LLC History Reduced 743,107 854 0.0% 0.0% 9 -72,224 -8.86% Q4 2025 Feb 17, 2026
RENAISSANCE TECHNOLOGIES LLC History Added to 728,380 837 0.0% 0.0% 10 +152,044 26.38% Q4 2025 Feb 12, 2026
Atle Fund Management AB History New 617,245 709 0.23% 11 +617,245 New Q4 2025 Feb 06, 2026
BANK OF AMERICA CORP /DE/ History Reduced 587,851 676 0.0% 0.0% 12 -28,071 -4.56% Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 577,211 664 0.0% 0.0% 13 +32,703 6.01% Q4 2025 Feb 09, 2026
Longaeva Partners L.P. History No change 503,214 578 0.05% 0.16% 14 0 0.0% Q4 2025 Feb 17, 2026
UBS Group AG History Added to 392,766 451 0.0% 0.0% 15 +19,039 5.09% Q4 2025 Jan 29, 2026
MARSHALL WACE, LLP History New 389,764 448 0.0% 16 +389,764 New Q4 2025 Feb 13, 2026
CITADEL ADVISORS LLC History Added to 378,189 434 0.0% 0.0% 17 +40,830 12.1% Q4 2025 Feb 17, 2026
Decheng Capital LLC History No change 326,810 375 0.05% 0.13% 18 0 0.0% Q4 2025 Feb 12, 2026
ExodusPoint Capital Management, LP History New 317,769 365 0.0% 19 +317,769 New Q4 2025 Feb 17, 2026
XTX Topco Ltd History Added to 289,033 332 0.01% 0.0% 21 +271,334 1533.05% Q4 2025 Feb 17, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 288,714 332 0.0% 0.0% 20 +129,683 81.55% Q4 2025 Feb 17, 2026
STATE STREET CORP History Added to 241,637 277 0.0% 0.0% 22 +39,582 19.59% Q4 2025 Feb 13, 2026
Point72 Asset Management, L.P. History New 188,136 216 0.0% 23 +188,136 New Q4 2025 Feb 17, 2026
Graham Capital Management, L.P. History New 183,942 211 0.01% 24 +183,942 New Q4 2025 Feb 17, 2026
Bank of New York Mellon Corp History No change 165,044 189 0.0% 0.0% 25 0 0.0% Q4 2025 Feb 10, 2026
Qube Research & Technologies Ltd History Added to 145,813 167 0.0% 0.0% 26 +115,005 373.3% Q4 2025 Feb 17, 2026
NewEdge Wealth, LLC History No change 116,006 133 0.0% 0.01% 27 0 0.0% Q4 2025 Feb 03, 2026
TWO SIGMA INVESTMENTS, LP History Added to 105,528 121 0.0% 0.0% 28 +59,027 126.94% Q4 2025 Feb 17, 2026
NORTHERN TRUST CORP History Added to 101,948 117 0.0% 0.0% 29 +1,175 1.17% Q4 2025 Feb 17, 2026
Quadrature Capital Ltd History New 100,536 115 0.0% 30 +100,536 New Q4 2025 Feb 17, 2026
MORGAN STANLEY History Reduced 89,222 102 0.0% 0.0% 31 -17,385 -16.31% Q4 2025 Feb 13, 2026
GOLDMAN SACHS GROUP INC History Reduced 86,145 99 0.0% 0.0% 32 -39,309 -31.33% Q4 2025 Mar 25, 2026
TORONTO DOMINION BANK History New 75,000 86 0.0% 33 +75,000 New Q4 2025 Feb 17, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History Reduced 72,700 83 0.0% 0.0% 34 -4,000 -5.22% Q4 2025 Feb 17, 2026
OMERS ADMINISTRATION Corp History New 67,000 77 0.0% 35 +67,000 New Q4 2025 Feb 13, 2026
Cable Car Capital, LP History No change 61,606 70 0.0% 0.06% 36 0 0.0% Q4 2025 Feb 17, 2026
BARCLAYS PLC History Added to 60,385 69 0.0% 0.0% 37 +57,424 1939.34% Q4 2025 Feb 13, 2026
ROYAL BANK OF CANADA History New 55,551 64 0.0% 38 +55,551 New Q4 2025 Feb 17, 2026
J. Derek Lewis & Associates Inc. History New 53,000 60 0.01% 39 +53,000 New Q4 2025 Mar 23, 2026
DIMENSIONAL FUND ADVISORS LP History Added to 50,066 57 0.0% 0.0% 40 +13,550 37.11% Q4 2025 Feb 12, 2026
UNIVERSITY OF CHICAGO History No change 48,731 56 0.03% 0.05% 41 0 0.0% Q4 2025 Feb 06, 2026
Velan Capital Investment Management LP History Reduced 40,000 46 0.03% 0.11% 42 -15,000 -27.27% Q4 2025 Feb 13, 2026
HRT FINANCIAL LP History Added to 39,649 45 0.0% 0.0% 44 +24,251 157.49% Q4 2025 Feb 12, 2026
COMMONWEALTH EQUITY SERVICES, LLC History Reduced 39,755 45 0.0% 0.0% 43 -21,400 -34.99% Q4 2025 Feb 12, 2026
LPL Financial LLC History Added to 35,102 40 0.0% 0.0% 45 +21,100 150.69% Q4 2025 Feb 11, 2026
AMERICAN CENTURY COMPANIES INC History New 31,936 36 0.0% 46 +31,936 New Q4 2025 Feb 13, 2026
Lighthouse Investment Partners, LLC History New 28,860 33 0.0% 47 +28,860 New Q4 2025 Feb 17, 2026
Avanza Fonder AB History New 27,345 31 0.0% 49 +27,345 New Q4 2025 Jan 12, 2026
Cetera Investment Advisers History Reduced 27,260 31 0.0% 0.0% 48 -500 -1.8% Q4 2025 Feb 17, 2026
Maia Wealth LLC History New 21,959 29 0.0% 50 +21,959 New Q4 2025 Feb 17, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 24,279 27 0.0% 0.0% 51 +22,562 1314.04% Q4 2025 Feb 10, 2026
TWO SIGMA ADVISERS, LP History Reduced 22,624 26 0.0% 0.0% 52 -29,900 -56.93% Q4 2025 Feb 17, 2026
Engineers Gate Manager LP History New 22,816 26 0.0% 53 +22,816 New Q4 2025 Feb 17, 2026
FOX RUN MANAGEMENT, L.L.C. History New 22,566 25 0.0% 54 +22,566 New Q4 2025 Feb 11, 2026
OSAIC HOLDINGS, INC. History Added to 17,224 19 0.0% 0.0% 55 +2,003 13.16% Q4 2025 Feb 17, 2026
Jefferies Financial Group Inc. History New 16,000 18 0.0% 56 +16,000 New Q4 2025 Feb 09, 2026
FMR LLC History Reduced 12,858 14 0.0% 0.0% 57 -2,597 -16.8% Q4 2025 Feb 17, 2026
PACES FERRY WEALTH ADVISORS, LLC History New 11,440 13 0.01% 58 +11,440 New Q4 2025 Feb 11, 2026
Tower Research Capital LLC (TRC) History Reduced 10,810 12 0.0% 0.0% 59 -2,172 -16.73% Q4 2025 Feb 17, 2026
NewEdge Advisors, LLC History Added to 10,250 11 0.0% 61 +10,000 4000.0% Q4 2025 Feb 18, 2026
SIMPLEX TRADING, LLC History Added to 9,790 11 0.0% 0.0% 60 +2,357 31.71% Q4 2025 Feb 11, 2026
China Universal Asset Management Co., Ltd. History Reduced 10,146 11 0.0% 0.0% 62 -725 -6.67% Q4 2025 Jan 29, 2026
BALYASNY ASSET MANAGEMENT L.P. History New 8,227 9 0.0% 63 +8,227 New Q4 2025 Feb 17, 2026
Winthrop Capital Management, LLC History No change 6,000 7 0.0% 0.0% 64 0 0.0% Q4 2025 Feb 10, 2026
JPMORGAN CHASE & CO History Added to 5,514 6 0.0% 0.0% 65 +1,001 22.18% Q4 2025 Feb 11, 2026
CITIGROUP INC History Added to 2,902 3 0.0% 0.0% 66 +1,621 126.54% Q4 2025 Feb 13, 2026
Mirae Asset Global Investments Co., Ltd. History Added to 3,026 3 0.0% 0.0% 67 +628 26.19% Q4 2025 Jan 26, 2026
WELLS FARGO & COMPANY/MN History Added to 2,285 2 0.0% 68 +2,000 701.75% Q4 2025 Feb 13, 2026
FEDERATED HERMES, INC. History New 1,894 2 0.0% 69 +1,894 New Q4 2025 Feb 12, 2026
GF FUND MANAGEMENT CO. LTD. History Reduced 1,277 1 0.0% 0.0% 72 -57 -4.27% Q4 2025 Jan 27, 2026
NISA INVESTMENT ADVISORS, LLC History No change 961 1 0.0% 0.0% 70 0 0.0% Q4 2025 Jan 15, 2026
Physician Wealth Advisors, Inc. History No change 943 1 0.0% 0.0% 71 0 0.0% Q4 2025 Jan 29, 2026
TANG CAPITAL MANAGEMENT LLC History Closed out 0 0 0.21% -2,500,000 -100.0% Q3 2025 Nov 14, 2025
PERCEPTIVE ADVISORS LLC History Closed out 0 0 0.08% -1,178,307 -100.0% Q3 2025 Nov 14, 2025
STEMPOINT CAPITAL LP History Closed out 0 0 0.31% -689,538 -100.0% Q3 2025 Nov 14, 2025
DRIEHAUS CAPITAL MANAGEMENT LLC History Closed out 0 0 0.01% -418,632 -100.0% Q3 2025 Nov 14, 2025
SCHULHOFF & CO INC History Closed out 0 0 0.26% -275,000 -100.0% Q3 2025 Nov 10, 2025
PIER 88 INVESTMENT PARTNERS LLC History Closed out 0 0 0.06% -151,730 -100.0% Q3 2025 Oct 31, 2025
DIADEMA PARTNERS LP History Closed out 0 0 0.09% -150,000 -100.0% Q3 2025 Nov 14, 2025
Walleye Capital LLC History Closed out 0 0 0.0% -119,561 -100.0% Q3 2025 Nov 14, 2025
ACADIAN ASSET MANAGEMENT LLC History Closed out 0 0 0.0% -43,082 -100.0% Q3 2025 Nov 13, 2025
Persistent Asset Partners Ltd History Closed out 0 0 0.05% -34,632 -100.0% Q3 2025 Jan 15, 2026
PRUDENTIAL FINANCIAL INC History Closed out 0 0 0.0% -16,300 -100.0% Q3 2025 Nov 13, 2025
AQR CAPITAL MANAGEMENT LLC History Closed out 0 0 0.0% -13,832 -100.0% Q3 2025 Nov 14, 2025
EverSource Wealth Advisors, LLC History Closed out 0 0 -434 -100.0% Q3 2025 Nov 10, 2025
CWM, LLC History Reduced 70 0 0.0% -344 -83.09% Q4 2025 Jan 26, 2026
Cornerstone Financial Management LLC History New 172 0 +172 New Q4 2025 Feb 13, 2026
US BANCORP \DE\ History New 94 0 +94 New Q4 2025 Jan 30, 2026
SBI Securities Co., Ltd. History Reduced 1 0 -1 -50.0% Q4 2025 Feb 03, 2026
JONES FINANCIAL COMPANIES LLLP History No change 500 0 0.0% 0 0.0% Q4 2025 Feb 17, 2026
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO History No change 12 0 0 0.0% Q4 2025 Feb 10, 2026
Arax Advisory Partners History No change 14 0 0 0.0% Q4 2025 Feb 13, 2026
Skaana Management L.P. History No change 73,130 0 0 0.0% Q4 2025 Feb 10, 2026